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The stage is set for a compelling Premier League contest as table-toppers Arsenal entertain bottom-placed Wolverhampton Wanderers to the Emirates Stadium.

Starting Lineups

Mikel Arteta's side have made a trio of alterations from the team that suffered a narrow loss at Villa Park in their previous outing. William Saliba, Viktor Gyökeres and the Brazilian winger all start in the starting eleven. The captain and Mikel Merino are named on the substitutes' bench, while the Italian defender is absent. The centre-back returns after missing a run of games due to injury.

The visitors also have made three changes to their starting XI following being soundly beaten 4-1 at Molineux by United on Monday evening. The experienced full-back, João Gomes and the South Korean forward come in. Ki-Jana Hoever and Jhon Arias are on the bench, while Bellegarde misses out altogether.

Confirmed Lineups

Arsenal: Raya, White, Saliba, Hincapie, Timber, Eze, Zubimendi, Rice, Saka, Gyokeres, Martinelli.
Bench: Arrizabalaga, Odegaard, Gabriel Jesus, Norgaard, Trossard, Madueke, Nwaneri, Merino, Lewis-Skelly.

Wolverhampton Wanderers: Johnstone, Mosquera, Agbadou, Toti Gomes, Doherty, Joao Gomes, Andre Trindade, Krejci, Wolfe, Larsen, Hwang.
Subs: Tchatchoua, Mane, Lopez, Hoever, Chirewa, Arokodare, Arias, Santiago Bueno, Jose Sa.

Match Official: Robert Jones
VAR Official: John Brooks

Preamble

Welcome! And I mean, look at this …

The standings reveals a stark contrast. Arsenal sit proudly at the top of the table, while Wolves occupy the bottom of the league.

… yet while this will be the 42nd occasion the Premier League leaders have taken on the team at the foot of the entire table – with 30 out of 41, with seven tied games – which team is responsible for two of the four historical shocks? Why, Wolverhampton Wanderers, of course! So while the Arsenal manager will undoubtedly be anticipating another victory, the Wolves boss must know that long shots sometimes succeed, and you never know. Kick-off is at 8 o'clock in the evening GMT. Let's go!

^{(The remaining last-over-first victories in the Premier League era are Oldham Athletic's 1-0 win over Manchester United in March 1993, and Spurs – admittedly, a surprising one - defeating Liverpool in November 2008.)}